Trustworthy AI · Biomedical AI · AI in Education

Xinxing Wu

AI researcher and educator building reliable, interpretable, and practical learning systems.

My research focuses on algorithmic stability, interpretable machine learning, feature selection, graph learning, biomedical AI, survival modeling, and AI-enhanced education. I am currently an Assistant Prof. of AI at KYSU.

About

Research · Open source · Teaching

I develop reproducible machine-learning methods and open-source AI systems for scientific, biomedical, and educational applications.

Certifications: Red Hat Certified Engineer (RHCE); Red Hat Certified System Administrator (RHCSA)

Research Areas

Three connected directions

Trustworthy Machine Learning

Algorithmic stability, generalization, feature selection, interpretable ML, and graph learning.

Biomedical AI

Machine learning for Alzheimer’s disease, LATE, transcriptomics, survival analysis, and progression modeling.

AI in Education

Open-source multimodal tools, virtual avatars, AI-assisted course materials, and student-centered learning.

Selected Publications

Representative work by area

Computer Science

  1. Stability-based Generalization Analysis of Distributed Learning Algorithms for Big Data
    Xinxing Wu, Junping Zhang, Wang Fei-Yue · IEEE Transactions on Neural Networks and Learning Systems, 2020
  2. Fractal Autoencoders for Feature Selection
    Xinxing Wu, Qiang Cheng · AAAI 2021
  3. Algorithmic Stability and Generalization of an Unsupervised Feature Selection Algorithm
    Xinxing Wu, Qiang Cheng · NeurIPS 2021
  4. Stabilizing and Enhancing Link Prediction through Deepened Graph Auto-Encoders
    Xinxing Wu, Qiang Cheng · IJCAI-ECAI 2022

Biomedical AI

  1. PRIME Uncovers Circadian Oscillation Patterns and Links with Alzheimer’s Disease in Untimed Genome-Wide Gene Expression Data across Multiple Regions of Human Brain
    Xinxing Wu, Chong Peng, Donna M. Wilcock, et al. · Alzheimer’s & Dementia, 2021
  2. Random Forest-Integrated Analysis in AD and LATE Brain Transcriptome-Wide Data to Identify Disease-Specific Gene Expression
    Xinxing Wu, Chong Peng, Peter T. Nelson, et al. · PLOS ONE, 2021
  3. Deep Learning Algorithm Reveals Probabilities of Stage-Specific Time to Conversion in Individuals with Neurodegenerative Disease LATE
    Xinxing Wu, Chong Peng, Peter T. Nelson, et al. · Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
  4. Machine Learning Approach Predicts Probability of Time to Stage-Specific Conversion of Alzheimer’s Disease
    Xinxing Wu, Chong Peng, Peter T. Nelson, et al. · Journal of Alzheimer’s Disease, 2022

AI in Education

  1. Designing Singing Syllabi with Virtual Avatars: AI-Assisted Syllabus Reauthoring
    Xinxing Wu · Open Scholarship of Teaching and Learning, 2026
  2. Talking Slide Avatars: Open-Source Multimodal Communication Approach for Teaching
    Xinxing Wu · Arts & Communication, 2026

Selected Open-Source Projects

Research code and teaching systems

FAE

Fractal Autoencoders for feature selection · AAAI 2021.

Repository ↗

UFS

Stability and generalization for unsupervised feature selection · NeurIPS 2021.

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DGAE

Deepened graph auto-encoders for link prediction · IJCAI 2022.

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AD_Survival

DeepSurv pipeline for clinical survival and progression analysis.

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SSVA

AI-assisted singing syllabi and virtual-avatar teaching materials.

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AI-Powered Education

Open-source AI-enhanced education projects and classroom experiments.

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Teaching Demos

Course websites, programming examples, and practical classroom demos.

Visit ↗

Teaching

Courses taught or designed

Midway University

Jan. 2023 – Dec. 2025

Computer Science · Undergraduate

  • CSE-150: Introduction to Computer Science · Teacher · Spring 2023, Spring 2024, Spring 2025
  • CSE-200: Computer Programming I · Teacher · Fall 2023
  • CSE-210: Computer Programming II · Designer & Teacher · Spring 2023, Spring 2024
  • CSE-250: Database Systems · Designer & Teacher · Spring 2023, Spring 2024, Spring 2025
  • CSE-300: Human-Computer Interaction · Designer & Teacher · Fall 2023, Fall 2024, Fall 2025
  • CSE-310: Platform Technologies · Designer & Teacher · Fall 2023, Fall 2024
  • CSE-320: Networking · Designer & Teacher · Spring 2024, Spring 2025
  • CSE-400: Cybersecurity · Designer & Teacher · Fall 2024, Fall 2025
  • CSE-410: Mobile Computing · Designer & Teacher · Fall 2024, Fall 2025
  • CSE-420: Emerging Technology · Designer & Teacher · Spring 2025
  • CSE-430: AI in Advanced Data Analytics · Designer · Spring 2025
  • CSE-490: Capstone · Designer & Teacher · Spring 2025
  • CSE-495: Internship · Designer & Teacher · Summer 2024

Management Information Systems · Graduate

  • MIS-502: Business Programming · Designer · Fall 2023
  • MIS-612 (Online): Data and Information Management · Designer & Teacher · Fall 2023
  • MIS-632: Intelligent Business Systems · Designer · Spring 2024; Teacher · Fall 2025
  • MIS-642: MIS Security · Designer · Spring 2024
  • MIS-652: Business Analytics · Designer · Fall 2023; Teacher · Fall 2025
  • MIS-662: Machine Learning in MIS · Designer · Fall 2023; Teacher · Fall 2025

Kentucky State University

Jan. 2026 – Present

Computer Science · Undergraduate

  • COS-107 (Hybrid): Prob Solving Logic & Design · Teacher · Fall 2026
  • COS-109: Prin Computer Sci II · Teacher · Spring 2026, Fall 2026
  • COS-200 (Online): Computer Information Systems · Teacher · Spring 2026
  • COS-310: Discrete Computing Structures · Teacher · Fall 2026
  • COS-340: Data Struc Algorithm Analy · Teacher · Spring 2026
  • COS-460: Artificial Intelligence · Teacher · Fall 2026
  • COS-475: Game Design and Development · Teacher · Spring 2026

Computer Science · Graduate

  • COS-502: Computer Science Foundation I · Teacher · Spring 2026, Fall 2026
  • COS-504: Computer Science Found II · Teacher · Fall 2026
  • COS-506 (Hybrid): Adv Programming/Data Structure · Teacher · Spring 2026
  • COS-537 (Hybrid): Artificial Intelligence · Teacher · Fall 2026

Professional Service

Academic community service

Program Committee Member: NeurIPS, ICML, AAAI, CVPR, IJCAI, ICLR, ICCV, ECCV, WACV, WWW, AMIA, etc.

Journal Reviewer: TMLR, CAAI Transactions on Intelligence Technology, Artificial Intelligence in Medicine, The Journal of Supercomputing, npj Dementia, Heliyon, etc.

Contact & Profiles

Research collaboration, open-source work, and teaching projects.

Collaboration 🤝